GnRH - Gonadotropin Releasing Hormone

"What is GnRH? Gonadotropin releasing hormone. The commercial product brand name is CYSTORELIN. Cystorelin is a sterile solution containing 50 micrograms of gonadorelin. Gonadorelin is the hypothalmic releasing factor responsible for the release of gonadotropins (e.g. FSH (follicle stimulating hormone) and LH (luteinizing hormone)), from the anterior pituitary. Synthetic gonadorelin is physiologically and chemically identical to the endogenous bovine hypothalmic releasing factor. Cystorelin has been shown to be safe. In the normal cycle of events the hypothalamus produces gonadorelin which is responsible for causing the anterior pituitary gland to release FHS and LH which cause development, maturation and rupture of the follicle, preparing the ova for conception." "If female is not ovulating, we can administer an intramuscular injection of GnRH to begin the cycle of ovulation. In five to seven days, we can measure the progesterone level in her blood and determine if she has ovulated. We can then plan an appropriate breeding schedule". "There are times when females develop follucular cysts, thus preventing conception. An intramuscular injection of GnRH in conjunction with manual rupture of the follicle has been effective in allowing the normal sequence of events to take place."